Saint Agnes of Montepulciano was born in 1268 into the noble Segni family in Gracciano. At the age of nine, she convinced her parents to allow her to enter a Franciscan monastery of women in the city known as the “Sisters of the Sack”, after the rough religious habit they wore. They lived a simple contemplative life. She received the permission of the pope to be accepted into this life at such a young age, which was normally against Church law. At the age of fourteen she was appointed bursar.
In 1288 Agnes, despite her youth at only 20 years of age, was noted for her devotion to the Blessed Sacrament and deep life of prayer, and was elected as the prioress of the community. There she gained a reputation for performing miracles; people suffering from mental and physical ailments seemed cured by her presence. She was reported to have “multiplied loaves”, creating many from a few on numerous occasions, recalling the Gospel miracle of the loaves and fishes. She herself, however, suffered severe bouts of illness which lasted long periods of time.
In 1306, Agnes was recalled to head the monastery in Montepulciano. Agnes reached a high degree of contemplative prayer and is said to have been favoured with many visions. By 1316, Agnes’ health had declined so greatly that her doctor suggested taking the cure at the thermal springs in the neighbouring town of Chianciano Terme. While many of the other bathers reported being cured of their illnesses, Agnes herself received no benefit from the springs. Agnes died the following 20 April, at the age of 49.