Blessed Melchior entered the Augistinian Order and received the Recollect habit at the young age of 18. In 1621, he left and set sail to the Philippines for his missionary work.
After his ordination in Mexico, they arrived at the monastery of Saint Nicholas in Manila. One of his duties in the Philippines was to preach to the people. In 1632, Blessed Melchior went to Japan to care for the Christians who were being persecuted there. However, he was reported to the Japanese officials by some of the people who helped transport him to Japan.
He was tortured and persecuted along with the other Christians. He died on December 11, 1632 when he was burned at the stake. He was beatified by Pope John Paul II on March 26, 1989.